The Science behind
Hypochlorous Acid in pureactil
What is Hypochlorous Acid?
Hypochlorous Acid is a naturally occurring molecule produced by your white blood cells (neutrophils) as part of the innate immune system. Working as a a potent oxidizer that destroys harmful microorganisms by disrupting their cell membranes, Hypochlorous Acid is nature’s way of fighting infections (1).
Cleanse & Balance
Hypochlorous Acid is scientifically proven to be broad-spectrum, meaning it effectively targets bacteria, fungi, and viruses (2, 3, 4).
Skin often harbors excess bacteria thriving on lipids called sebum, in the sebaceous glands. Studies show that similar ingredients like Sodium
Hypochlorite(the base pair of Hypochlorous Acid) significantly reduce pimples and pustules in mild to moderate acne (5). Hypochlorous Acid is a gentle yet effective solution to naturally balance breakout-prone skin — without harsh chemicals in high concentrations.
Anti-inflammatory Effect: Calm & Soothe
Hypochlorous Acid isn’t just antimicrobial — it’s also a powerful anti-inflammatory. Research shows that Hypochlorous Acid modulates key inflammatory mediators like IL-12 and TNF-alpha, helping to reduce skin redness, irritation, and flare-ups (6). By calming the skin’s natural responses, Hypochlorous Acid helps prevent the long-term damage caused by inflammation.
References:
- Ulfig, A., & Leichert, L. I. (2021). The effects of neutrophil-generated hypochlorous acid and other hypohalous acids on host and pathogens. Cellular and Molecular Life Sciences, 78, 385–414.
- Zhao, K., Hu, F., Zhang, Z., Yin, X., Wang, H., & Li, M. (2023). 0.01% Hypochlorous acid treats Aspergillus fumigatus keratitis in rats by reducing fungal load and inhibiting the inflammatory response. Translational Vision Science & Technology, 12(8), 3.
- Hakim, H., Thammakarn, C., Suguro, A., Ishida, Y., Kawamura, A., Tamura, M., Satoh, K., Tsujimura, M., Hasegawa, T., & Takehara, K. (2015). Evaluation of sprayed hypochlorous acid solutions for their virucidal activity against avian influenza virus through in vitro experiments. Journal of Veterinary Medical Science, 77(2), 211–215.
- Chen, C. J., Chen, C. C., & Ding, S. J. (2016). Effectiveness of hypochlorous acid to reduce the biofilms on titanium alloy surfaces in vitro. International Journal of Molecular Sciences, 17(7), 1161.
- Dorostkar, A., Ghahartars, M., Namazi, M., Todarbary, N., Hadibarhaghtalab, M., & Rezaee, M. (2021). Sodium hypochlorite 0.005% versus placebo in the treatment of mild to moderate acne: A double-blind randomized controlled trial. Dermatology Practical & Conceptual, 11(3), e2021046.
- Fukuyama, T., Martel, B. C., Linder, K. E., Ehling, S., Ganchingco, J. R., & Bäumer, W. (2018). Hypochlorous acid is antipruritic and anti-inflammatory in a mouse model of atopic dermatitis. Clinical and Experimental Allergy, 48(1), 78–88.